Low High-Density Lipoprotein and Risk of Myocardial Infarction

نویسندگان

  • A. Ramirez
  • P. P. Hu
چکیده

Low HDL is an independent risk factor for myocardial infarction. This paper reviews our current understanding of HDL, HDL structure and function, HDL subclasses, the relationship of low HDL with myocardial infarction, HDL targeted therapy, and clinical trials and studies. Furthermore potential new agents, such as alirocumab (praluent) and evolocumab (repatha) are discussed.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

فراوانی فاکتورهای خطر آترواسکلروز در فرزندان افراد مبتلا به سکته‌ی قلبی زودرس

Background and objectives: Clinical manifestations of coronary artery disease such as myocardial infarction generally have onset from middle age onwards. However, studies indicate that the atherosclerotic process begins to develop during childhood. The purpose of this study was to evaluate the frequency of risk factors for atherosclerosis in children with family history of premature myocardial ...

متن کامل

Prevalence of Cardiovascular Risk Factors, Reperfusion Therapy and Mortality in Patients With ST-Elevation Myocardial Infarction in Elderly and Middle-ages

Objectives The prevalence of cardiovascular risk factors is different in the elderly and middle-aged. Therefore the present study aims to compare the prevalence of risk factors affecting ST-elevation myocardial infarction (STEMI), type of treatment, and mortality rate in these two groups. Methods & Materials This retrospective cohort study included 1 071 elderly and middle-aged ST-elevation my...

متن کامل

بررسی شیوع آنفارکتوس میوکارد خاموش و عوامل مرتبط با آن

ABSTRACT To clarify the prevalence and associated risk factors of silent transmural myocardial infarction (SMI), we examined a consecutive series of 1390 patients (mean age 56.6 years, male 70.9 percent, female 29.1 percent) with diagnosis of transmural myocardial infarction (MI) by resting ECG (with or without previous history of MI).during a period of six years in a cardiovascular private cl...

متن کامل

الگوی تغییرات سنی اولین سکته قلبی حاد در رفسنجان، طی سال‌های 1382 تا 1391: آیا سن کاهش یافته؟

Background and Objective: Age increase is known as a risk factor for cardiovascular disease and acute  myocardial infarction (AMI), but younger women and men are also at risk. The aim of this study was to evaluate the age changes of first AMI and risk factors affecting the patients admitted to the cardiac care unit of Ali- ibn- Abi Talib  hospital in Rafsanjan during the years 2003 to...

متن کامل

No-Reflow Phenomenon in Patients with ST-Elevation Acute Myocardial Infarction, Treated with Primary Percutaneous Coronary Intervention: A Study of Predictive Factors

  Introduction: No-reflow phenomenon in coronary vessels, manifested in some patients with reperfused acute myocardial infarction (MI), is associated with poor clinical and functional outcomes. Therefore, evaluation of predisposing risk factors can be helpful in risk assessment and identification of patients at higher risk. Herein, we aimed to study the predictive factors for the development of...

متن کامل

Oxidised LDL in Acute Myocardial Infarction: A Case-Control Study

Introduction: The metabolism of many fats, including free fatty acids and oxidized low density lipoprotein (ox-LDL) play an important role in the development of atherosclerosis. The aim of this study was to determine the association between circulating ox-LDL and acute myocardial infarction. Materials and Methods: The case control study conducted on 43 patients with acute myocardial infarction ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2015